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Staff Data Engineer (Menlo Park, CA or Durham, NC) #4433
Grail
Software Engineering, Data Science
Menlo Park, CA, USA
USD 163k-216k / year + Equity
Posted on Nov 8, 2025
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit grail.com.
GRAIL processes patient blood samples in factory-like laboratories to detect cancer. Engineering teams are tasked with building software and hardware to automate, analyse and streamline many processes in the lab. Additionally, Operations need metrics and insights into how things are running so that they can be improved. The data for some of these metrics have historically been built by Analysts within Operations. These are now moving under Software Engineering and we are building a team to support, stabilize and enhance these pipelines
We will hire candidates for this hybrid role in either Menlo Park, CA or Durham, NC.
Responsibilities
- Be a part of a highly collaborative team focused on delivering value to cross-functional partners by designing, deploying, and automating secure, efficient, and scalable data infrastructure and tools—reducing manual efforts and streamlining operations.
- Help model Grail data to ensure it follows FAIR principles (Findable, Accessible, Interoperable, and Reusable).
- Drive the design, deployment, and automated delivery of data infrastructure, standardized data models, datasets, and tools.
- Integrate automated testing and release processes to improve the quality and velocity of software and data deliveries.
- Collaborate with cross-functional teams—ranging from Research to Clinical Lab Operations to Software Engineering—to provide comprehensive data solutions from conception to delivery.
- Ensure all software and data meet high standards for quality, clinical compliance, and privacy.
- Mentor fellow engineers and scientists, promoting best practices in software and data engineering.
Preferred Qualifications
- B.S. / M.S. in a quantitative field (e.g., Computer Science, Engineering, Mathematics, Physics, Computational Biology) with 8+ years of related industry experience, or Ph.D. with at least 5 years of related industry experience or equivalent.
- Extensive experience developing with relational databases, data modeling principles, data pipeline tools, and workflow engines (e.g., SQL, DBT, Apache Airflow, AWS Glue, Spark).
- Extensive experience with DevOps practices, including CI/CD pipelines, containerized deployment (e.g., Kubernetes), and infrastructure-as-code (e.g., Terraform).
- Experience supporting data science and machine learning data pipelines, preferably in the context of biological data analysis and using Python.
- Ability to embrace uncertainty, navigate ambiguity, and collaborate with product teams and stakeholders to refine requirements and drive toward clear engineering objectives and designs.
- You are a strong written and verbal communicator and can adapt your communication style and the level of detail to your audience.
Expected full time annual base pay scale for the bay area is $163K-$216K. Actual base pay will consider skills, experience and location.
Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.
In addition, GRAIL offers a competitive benefit package, including flexible time-off, a 401(k) with a company % match, medical, dental, and vision insurance plans, and carefully selected mindfulness offerings, in accordance with our applicable plans and policies. Learn more about our benefits here: px.sequoia.com/grail
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. It is GRAIL policy to provide equal employment opportunities without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, marital status, protected veteran status, disability status, medical condition, or any other class or characteristic protected by applicable federal, state, and local laws.
This policy applies to all phases of employment, including, but not limited to: recruiting, hiring, training, promotion, and termination at all levels of employment. GRAIL maintains a drug-free workplace.
Additionally, GRAIL will consider all qualified job-seekers with criminal histories in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
We welcome job-seekers from all backgrounds to join us!